GLP-1
Compliance & Safety Protocol
FOR RESEARCH PURPOSES ONLY. NOT FOR HUMAN USE.
Research Profile
What is GLP-1?
GLP-1 (glucagon-like peptide-1, 7-37) is the biologically active form of the endogenous incretin hormone glucagon-like peptide-1, derived from proglucagon cleavage. With the molecular formula C₁₅₁H₂₂₆N₄₀O₄₆ and a molecular weight of 3337.73 g/mol (CAS: 106612-94-6), it is a 31-amino-acid peptide studied in pancreatic beta-cell and incretin-pathway models for its interactions with the GLP-1 receptor and downstream Gs-protein coupled cAMP signaling.
His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-GlySpecifications
| CAS Number | 106612-94-6 (GLP-1 7-37) |
| Molecular Formula | C151H226N40O46 |
| Molecular Weight | 3337.73 g/mol |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | -20 °C, lyophilized |
| Shipping | Insulated packaging |
Mechanism of Action
GLP-1 Receptor
Receptor interactionPublished research demonstrates GLP-1 modulates targeted signaling cascades within cell tissue models.
Gs-protein coupled signaling
Signaling cascadeIn cellular environments, GLP-1 exhibits selective binding and corresponding pathway activation.
Storage & Handling
Related Compounds
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Ancillary Compounds
Scientific Context
Related Research & Analysis
GLP-2-T
What Is GLP-2-T? Tirzepatide Naming, the GLP-2 Label Collision, and Dual-Agonist Pharmacology
GLP-2-T is a research-market label for tirzepatide, a synthetic dual GIP and GLP-1 receptor co-agonist (C₂₂₅H₃₄₈N₄₈O₆₈, 4813.5 g/mol, CAS 2023788-19-2). It has nothing to do with the intestinal hormone GLP-2. Where the label came from, why it collides with real hormone nomenclature, and what the receptor pharmacology actually is. For research purposes only.
Retatrutide
Retatrutide: Molecular Structure, Triple-Agonist Pharmacology, and Research Overview
A research overview of Retatrutide, a synthetic triple-agonist peptide studied for its simultaneous activity at GLP-1, GIP, and glucagon receptors — representing a distinct pharmacological profile from single- and dual-agonist compounds in the incretin class. For research purposes only.
GLP-1
DPP-4 and Why Native GLP-1 Falls Apart So Fast
Native GLP-1 has a circulating half-life of roughly one to two minutes because a single enzyme cuts it two residues in. The enzymology behind that, why position 8 is the whole story, and how analog design works around it. For research purposes only.